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  • Who we serve
    • Academia
      Explore BioLegend

      Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

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  • Products
    • Research & Development
      • Genomic Analysis
        • IncRNA in Functional Studies
        • Nucleic Acid Isolation
        • NGS Workflows
        • Microplate Readers
        • Microfluidic Nucleic Acid Analysis
        • CRISPR Technologies
        • RNA Interference
        • Transfection and Ancillary Reagents
        • Oligonucleotide Custom Synthesis
        • cDNAs and ORF Clones
        • Single-Cell Sequencing
        • Labeled Nucleotides
        • qPCR
        • Library Prep Kits
        • Magnetic Beads
        • Viral Vector Products
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      • Protein Analysis
        • Binding Assays
        • Immunoassays
        • Microfluidic Protein Characterization
        • Microplate Readers
        • Microplates
        • Recombinant Proteins
        • Western Blotting
        • Sample Dissociation
        • M-PVA Magnetic Beads
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      • Cell Analysis
        • Cell Isolation
        • Cell Lines & Stem Cells
        • Cell Counting and Image Cytometry
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        • Cellular Imaging & Analysis
        • Immunoassays
        • In Vivo Imaging
        • Microplates
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      • Research Solutions
        • Immunoassays Solutions
        • pHSense Reagents
        • Biomarker Discovery
        • Cell and Gene Therapy
        • GMP Workflows
        • Biologics
        • Small Molecule Drug Discovery
        • Disease Research
        • Target Class
        • Drug Development
        • Precision Medicine Research
        • Functional Genomic Screening Solutions
        • Assay Development Workflows
        • Microphysiological Systems
        • Biobanking Workflows
        • Agrigenomics Workflows
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    • Clinical & Diagnostics
      • Reproductive Health
        • Maternal and Prenatal Testing
        • Revvity Genomics Software
        • Newborn Screening
        • Newborn Sequencing Research
        • Pregnancy-Relevant Infections
        • Endocrine Reproductive
        • Cell-free DNA Analysis
        • Neonatal Research
        • Preimplantation Genetic Testing
        • PlGF Testing Research
        • Molecular Cytogenetics
        New IVD Mimix™ reference standards for oncology workflows.

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      • Infectious Diseases
        • Tuberculosis Management
        • EUROIMMUN Solutions
        • IDS Solutions
        • Nucleic Acid Isolation for Pathogen Detection
        • Cytomegalovirus
        • SARS-COV-2 Testing Solutions
        • Bacterial & Viral Nucleic Acid Isolation
        • Metagenomics
        New IVD Mimix™ reference standards for oncology workflows.

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      • Cancer
        • ASR Flow Cytometry Antibodies
        • HPV Testing
        • ctDNA Workflows
        • miRNA-seq Analysis
        • Exosome/cfRNA Analysis
        • Targeted Sequencing
        • Mimix Reference Standards
        • Functional Testing
        NEW! Mimix IVD reference standards

        Providing diagnostic labs with trusted quality controls for developing tests and monitoring workflows, with the added assurance of IVD marking. Explore our newest MimixTM controls.

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      • Autoimmunity
        • EUROIMMUN Solutions
        • IDS Solutions
        New IVD Mimix™ reference standards for oncology workflows.

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      • Endocrinology
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      • Allergy
        New IVD Mimix™ reference standards for oncology workflows.

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      • Neurodegeneration
        • Alzheimer's Disease
        • Amytrophic Lateral Sclerosis (ALS)
        • Neurogranin
        • BACE1
        New IVD Mimix™ reference standards for oncology workflows.

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      • Rapid Patient Testing
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      New IVD Mimix™ reference standards for oncology workflows.

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    • Reagents
      • BioLegend
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      • Cellular Imaging Reagents
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      • chemagic Nucleic Acid Purification Kits
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      • CRISPR Technologies
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      • GPCR Research Reagents
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      • Immunoassays
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      • In Vivo Imaging Reagents
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      • Liquid Scintillation Cocktails
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      • NGS Library Prep Kits
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      • pHSense Reagents
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      • qPCR
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      • Radiochemicals
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      • RNA Interference
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    • Platforms & Automation
      • Nucleic Acid Purification
        • chemagic Applications
        • chemagic IVD Instruments
        • chemagic IVD Kits
        • chemagic Instruments
        • chemagic Kits
        • M-PVA Magnetic Beads
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Automated Liquid Handling
        • Flow Cytometry Cocktail Prep Automation
        • Liquid Handling Workstations
        • Automated Liquid Handling Applications
        • Liquid Handling Consumables & Accessories
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Integrated Lab Automation
        • Automated Plate Loading
        • Workstation Modules
        • Scheduling & Control Software
        • Robotics
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Microfluidic Analysis
        • Microfluidic Protein Characterization
        • Microfluidic Nucleic Acid Analysis
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Detection Solutions
        • Plate Reader Accessories
        • Microplate Readers
        • Radiometric Detectors
        • Radiochemicals
        • Liquid Scintillation Cocktails
        • Radiometric Consumables & Accessories
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Imaging
        • Cellular Imaging & Analysis
        • In Vivo Imaging
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Cell Counting and Image Cytometry
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Sample Homogenization
        • Homogenizers
        • Homogenizer Accessories
        • Homogenizer Consumables
        • Sample Centrifugation
        • Sample Sonication
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • In Vitro Diagnostics (IVD) Platforms & Automation
        • IVD Nucleic Acid Isolation
        • IVD Automated Liquid Handling
        • IVD Radiometric Detectors
        • EUROIMMUN Instruments
        • IDS Instruments
        • Clinical Applications
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Consumables & Accessories
        • Cassettes
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        • High-Content Imaging Accessories
        • Microplates
        • Radioactive Spill Cleaners
        • Scintillation Cocktails
        • Transfer Membranes
        • Charcoal Traps
        • Homogenizer Accessories
        • Homogenizer Consumables
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Instrument Service & Maintenance
        • On Demand Equipment Service
        • Equipment Service Plans
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      New! Cellometer™ Ascend™

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    • Consumables & Accessories
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    • Signals Software
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        • ChemDraw
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        • Signals Clinical
        • Signals Notebook
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      • All Solutions
        • Biology
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        • Clinical & Translational
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        • Food/Flavor/Fragrance
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  • Services
    • Preclinical Services
      • Antibody Drug Conjugate Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Complex Cell Model Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Base Editing Platform
        • Pin-point base editing platform cell line engineering services
        • Pin-point base editing platform pooled tiled screening services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Immune Cell Screening
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Functional Genomic Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Cell Panel Screening
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Cell Line Engineering
        • CHOSOURCE CLE Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Viral Vector Engineering and Manufacture
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      Preclinical services

      Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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    • Revvity Omics Services
      • Revvity Omics Clinical Services
        • Cytogenomics
        • Global Laboratory Network
        • Metabolic Testing
        • Newborn Screening Services
        • Prenatal Screening Services
        • Proactive Testing
        • Rare Disease Testing
        • Specialized and Customized Assays
        • Sponsored Testing Programs
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Clinical & Testing Services
      • Revvity Omics Clinical Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Cellular and Humoral Immunoassays
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Tuberculosis Testing Services
        • Oxford Diagnostic Laboratories Service Closures
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customization Services
      • Assays and Reagents
        • Assay Development
        • Compound profiling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Microplate Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Custom Conjugation & Labeling
        • Custom Labeling
        • Small Molecule
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Radiosynthesis and Labeling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Licensing
      • Gene Delivery Licensing
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Gene Expression Systems
        • AAV Production Platform
        • CHOSOURCE Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Pin-point™ Base Editing Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Virus Screening
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      CHOSOURCE expression platform

      Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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    • Viral Vector Engineering and Manufacture
      • AAV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Lentivirus Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Instrument Service & Maintenance
      • AV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Equipment Service Plans
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • On-demand Equipment Service
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customer Training
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • OEM Solutions
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    T-SPOT.TB testing services.

    Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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  • Company
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    • Investor Relations
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        Investor Day 2024

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      Investor Day 2024

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  • Brands
      Revvity Brands
    • BioLegend

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    • Revvity Omics

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    • Tulip Diagnostics

    • ViaCord

    • Popular Revvity Product Brands
    • AlphaLISA and SureFire Ultra

    • BioQule NGS

    • chemagic

    • EnVision Nexus

    • Fontus

    • HTRF

    • IVIS

    • LEGENDplex

    • Opera Phenix

    • T-SPOT

    • TotalSeq

    • View all Revvity brands
  • Welcome to Revvity: renowned brands and boundless innovation.

    Hearing the word "can't" is our call to action!

    We help scientists, researchers, and clinicians overcome the world's greatest health obstacles.

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    Featured brand: BioLegend

    Learn about our world-class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

    Visit BioLegend.com

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  • Omni Bead Ruptor 12 Bead Mill Homogenizer

Omni Bead Ruptor 12 Bead Mill Homogenizer

Processing up to 12 x 2mL and 4 x 7 mL samples per batch, this mid-throughput benchtop unit supports sample volumes from 25 µL to 7 mL in their respective tube sizes, with processing speeds up to 6 m/s. It features front-loading tube holders and patent-pending snap-in carriage for simple operation, as well as optimized bead-beating motions and easy programming for cycle and dwell settings.

For research use only. Not for use in diagnostic procedures.
Part #: 19-050A
Sample Volume:
25 µL to 7 mL
Total list price:
USD 6,240.00
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Omni Bead Ruptor 12 bead mill homogenizer
Omni Bead Ruptor 12 bead mill homogenizer
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Omni Bead Ruptor 12 Bead Mill Homogenizer
Omni Bead Ruptor 12 bead mill homogenizer
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Omni Bead Ruptor 12 bead mill homogenizer
Omni Bead Ruptor 12 bead mill homogenizer
Omni Bead Ruptor 12 Bead Mill Homogenizer
Omni Bead Ruptor 12 bead mill homogenizer
Omni Bead Ruptor 12 bead mill homogenizer
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Product variant

25 µL to 7 mL
Sample Volume: 25 µL to 7 mL
Part #: 19-050A
List price: USD 6,240.00
Your online price: Log in to view
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Product information

  • Overview
  • Additional product information
  • Specifications
  • Video gallery
  • References

Overview

Bead Ruptor 12 homogenizer unleash power, performance and impact

For: Diverse sample types, genomic DNA, RNA, protein extraction, and small sample sizes

Throughput: Designed for medium throughput needs, accommodating up to 12 samples

Level up your lab with robust performance and economic advantage

Put performance at your fingertips with Bead Ruptor 12

The Bead Ruptor 12 stands amongst powerful bead mill homogenizers, offering a blend of power and economy. Designed for labs where time, cost, and reliability are of the essence, BR 12 redefines the standards of sample processing.

Unprecedented power

A powerful and cost-effective bead mill, the Omni Bead Ruptor 12 allows you to process up to 16 tubes at a time. Handling nearly any grinding, lysing, and homogenization tasks you throw at it, BR 12 preserves the integrity of your biological samples for exceptional molecular extraction

Customer-centric adaptability at your fingertips

Amazing impact: The Bead Ruptor 12 boasts an innovative tube carriage motion, reducing swirl and significantly increasing bead impact force, enhancing processing efficiency.

Broad speed range: Versatility is at the heart of our design, allowing you to process various samples with speed adjustments that cater to your specific needs.

Say goodbye to screwing down finger plates: Our patent-pending tube carriage streamlines your workflow, allowing for quick and secure tube placement, enhancing throughput and safety - a revolutionary step in homogenization technology.

Amplified throughput: With the capacity to homogenize up to 12 x 2 mL tubes or 4 x 7 mL tubes, workflow efficiency is not just improved—it’s transformed.

User-centric design: Our unique inclined carriage maximizes user control, power, and sample processing efficacy.

Endless operation: Say goodbye to downtime with no-cool-down requirement, priming your lab for continuous operation.

Sterility and safety: Disposable tubes support sample integrity, and an integrated lid lock enhances safety, securing your peace of mind.

Smart economics: Superb performance comes with an attractive price point, making it a prudent investment for any lab.

Minimal maintenance: The Omni advantage

We take pride in crafting our Bead Ruptor range with attention to durability. Each Bead Ruptor, manufactured right here in the United States, is built from robust materials, ensuring not just performance but also longevity and reliability.

Our commitment means that our homogenizers require minimal maintenance, even in the most demanding lab environments. When you choose an Omni Bead Ruptor, you're investing in a tool that's designed to last, delivering consistent results with every use.

Experience the peace of mind that comes with a product that's not just effective, but enduring.

Maintenance-free: Invest your resources in science, not upkeep. The Bead Ruptor 12 requires no maintenance, offering relentless performance day in and day out.

Ease of use: Experience an intuitive interface with a learning curve so slight it feels like second nature within minutes.

Adaptable for all: From life sciences to environmental studies, the Bead Ruptor 12’s flexibility makes it an invaluable asset across numerous industries

Level up your lab today

Unlock the full potential of your lab with the Bead Ruptor 12. It’s not just a homogenizer; it’s a gateway to seamless sample preparation.

Additional product information

"The [Omni] Bead Ruptor uses a complex motion which we find highly effective. In the past, we have used other types of oscillating machines which have a back-and-forth motion along one dimension [which] can be a problem with certain sample volumes, such that the sample (beads plus yeast plus buffer) stays in essentially the same place, while the tube oscillates around it."1



Omni Bead Ruptor 12 homogenizer features

Specifications

Dimensions 38.1 cm (W) x 43.2 cm (D) x 33.0 cm (H)
Voltage
115 - 230V
Weight
29.0 kg
Accreditations
CE
Cycles/Programs
1 to 10 Cycles 99 Programs
Sample Volume
25 µL to 7 mL
Speed
0.8 - 6 m/s in increments of 0.15 m/s
Timer
1 second to 9:59 minutes
Warranty
1 Year

Video gallery

Omni Bead Ruptor 12 Bead Mill Homogenizer
Omni Bead Ruptor 12 Bead Mill Homogenizer

References

  1. Honey, S., & Futcher, B. (2025). A Trizol-Beadbeater RNA extraction method for yeast, and comparison to Novogene RNA extraction. bioRxiv, 2025-07.

Resources

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  • Application Note (3)
  • Infographic (1)
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1-3 of 3 Resources
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Application Note
DNA extraction from cannabis sativa using the Omni Bead Ruptor 12
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Application Note
Evaluation of protein extraction efficiency from hard tissues using the Omni Bead Ruptor 12 bead mill homogenizer

The efficiency of tissue homogenization is an important consideration upstream of many basic and pre-clinical research...

Learn more
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Application Note
High-throughput RNA extraction from Mus musculus tissues on the Omni Bead Ruptor 12 bead mill homogenizer

We evaluated the Omni Bead Ruptor 12 bead mill homogenizer’s ability to prepare various tissues - kidney, liver, heart, and lung...

Learn more

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