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IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)

Name: IVISense Pan Cathepsin 680 Fluorescent Probe (ProSense 680)
Price: 581.26 USD
Availability: InStock

Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time.

Revvity’s IVISense™ Pan Cathepsin fluorescent probes (ProSense®) are versatile pan-cathepsin-activatable NIR agents for imaging various disease-related events. These activatable probes are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation.

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Feature	Specification
Unit Size	1 vial (10 doses)
Specificity	Cathepsin proteases

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Product variants

Wave Length: 680 nm

Part #:

NEV10003

List price

USD 581.26

Your online price:

Wave Length: 750 nm

Part #:

NEV10001EX

List price

USD 612.39

Your online price:

Wave Length: 750 nm

Style

FAST

Part #:

NEV11171

List price

USD 676.29

Your online price:

For research use only. Not for use in diagnostic procedures.

Total list price:

USD 581.26

Product information

Overview

IVISense Pan Cathepsin 680 is our original “Smart” cathepsin probe; rather than targeting all protease, smart probes become fluorescent only after enzymatic cleavage, which keeps background down and allows detection of activated protease. 24h imaging at 680 nm.

Specifications

Other specifications

Brand	IVISense
Fluorescent Agent Type	Enzyme activated
Imaging Modality	Fluorescence
Shipping Conditions	Shipped in Blue Ice
Specificity	Cathepsin proteases
Storage Conditions	+2 to +8 °C
Therapeutic Area	Arthritis Atherosclerosis Inflammation Oncology Pulmonary Vascular
Unit Size	1 vial (10 doses)
Wave Length	680 nm