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  • Home
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  • Imaging
  • In Vivo Imaging
  • In Vivo Imaging Reagents
  • IVISense Fluorescent Probes
  • IVISense MMP 680 Fluorescent Probe (MMPSense)

IVISense MMP 680 Fluorescent Probe (MMPSense)

IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense MMP 680 Fluorescent Probe (MMPSense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes

Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

Revvity’s IVISense™ MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

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Feature Specification
Unit Size 1 vial (10 doses)
Specificity Matrix Metalloprotease
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Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

Revvity’s IVISense™ MMP NIR activatable fluorescence probes (MMPSense®) are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

View product information
Product variants
Wave Length: 645 nm
Part #:
NEV10100
List price
USD 706.60
Your online price:
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Wave Length: 680 nm
Part #:
NEV10126
List price
USD 702.04
Your online price:
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Wave Length: 750 nm
Part #:
NEV10168
List price
USD 702.04
Your online price:
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For research use only. Not for use in diagnostic procedures.
Total list price:
USD 702.04
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IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense MMP 680 Fluorescent Probe (MMPSense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense MMP 680 Fluorescent Probe (MMPSense)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
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Product information

  • Overview
  • Specifications

Overview

IVISense MMP 680 is excited by 680 + 10 nm excitation light, and emits at 700 + 10 nm. MMP 680 has an optimal imaging window of 24-36 hours after injection, allowing workflow flexibility in acquiring data in large animal cohorts. Including IVISense MMP 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

Specifications

Brand
IVISense
Fluorescent Agent Type
Enzyme activated
Imaging Modality
Fluorescence
Shipping Conditions
Shipped in Blue Ice
Specificity
Matrix Metalloprotease
Storage Conditions
+2 to +8 °C
Therapeutic Area
Arthritis
Atherosclerosis
Bone loss
Cardiovascular
Inflammation
Oncology
Pulmonary
Vascular
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Resources

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  • Application Brief (1)
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1-1 of 1 Resources
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Literature - Publication Review
The tobacco-specific carcinogen-operated calcium channel promotes lung tumorigenesis via IGF2 exocytosis in lung epithelial cells
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