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  • In Vivo Imaging
  • In Vivo Imaging Reagents
  • IVISense Fluorescent Probes
  • IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)

IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)

IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes

IVISense™ Folate Receptor 680 fluorescence imaging probe (FolateRSense™) is highly specific and sensitive in its detection of Folate Receptor alpha (FRa).

Used with in vivo imaging systems such as Revvity's industry leading IVIS® platform, this targeted probe enables the non-invasive visualization and quantification of FR expression in highly metabolic cells such as tumor cells.

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Feature Specification
Unit Size 1 vial (10 doses)
Specificity Folate receptor
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IVISense™ Folate Receptor 680 fluorescence imaging probe (FolateRSense™) is highly specific and sensitive in its detection of Folate Receptor alpha (FRa).

Used with in vivo imaging systems such as Revvity's industry leading IVIS® platform, this targeted probe enables the non-invasive visualization and quantification of FR expression in highly metabolic cells such as tumor cells.

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Product variant
Wave Length: 680 nm
Part #:
NEV10040
List price
USD 595.35
Your online price:
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For research use only. Not for use in diagnostic procedures.
Total list price:
USD 595.35
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IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes - optimized and validated on Revvity's IVIS® optical imaging platform
IVISense Folate Receptor 680 Fluorescent Probe (FolateRSense 680)
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
IVISense™ fluorescent imaging probes
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Product information

  • Overview
  • Specifications

Overview

Folate receptors are a family of cell surface receptors that bind the essential vitamin folic acid (folate, vitamin B9). These receptors are upregulated in highly metabolic cells and over-expression of FRA protein is associated with tumor growth, as uptake of folic acid is a necessary part of tumor metabolism.

Folate is essential for cellular metabolism and DNA synthesis, methylation, and repair. High metabolic cells such as proliferating cancer cells have increased demand for folate to maintain their accelerated DNA synthesis; thus overexpression of folate receptors (FRs) is a recognized biomarker of many tumors, though tumors can differ in their dependence on folate metabolism.

Specifications

Brand
IVISense
Fluorescent Agent Type
Targeted
Imaging Modality
Fluorescence
Shipping Conditions
Shipped Ambient
Specificity
Folate receptor
Storage Conditions
+2 to +8 °C
Therapeutic Area
Arthritis
Cardiovascular
Inflammation
Oncology
Pulmonary
Unit Size
1 vial (10 doses)
Wave Length
680 nm

Resources

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1-6 of 7 Resources
Flyer Icon
Flyer
Best practices for designing an effective in vivo fluorescence imaging study

Fluorescence molecular imaging is the visualization of cellular and biological function in vivo to gain deeper insights into...

Learn more
Application Brief Icon
Application Brief
Characterization of NIR fluorophores for their potential in non-specific tissue accumulation
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eBook Icon
eBook
In vivo imaging solutions

Researchers trust our in vivo imaging solutions to give them reliable, calibrated data that reveals pathway characterization and...

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Guide Icon
Guide
IVISense fluorescent probe selector guide for oncology research

The goal of in vivo fluorescence molecular imaging is to enable non-invasive visualization and quantification of cellular and...

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Poster Icon
Scientific Poster
Novel optical 2D image acquisition and analysis of tumor metastasis using the MVI-2 two-mouse, 360-degree positioning device
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Protocol/SOP
Protocol/SOP
SOP: IVISense Folate Receptor 680 (NEV10040) for in vivo imaging
Learn more
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