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IVIS Spectrum 2 In Vivo Imaging System
This product replaces the IVIS Spectrum system (part number 124262).
As the leader in optical imaging with thousands of publications using our flagship IVIS® Spectrum platform, the IVIS Spectrum 2 system is the next generation in optical imaging. Designed with an innovative camera with patented coating that delivers high sensitivity 2D and 3D bioluminescence and fluorescence imaging capabilities - the IVIS Spectrum 2 gives you the flexibility you need for your in vivo imaging studies.
For research use only. Not for use in diagnostic procedures.
Product information
Overview
Building upon the IVIS Spectrum in vivo optical system with proven 2D bioluminescence and 2D fluorescence imaging and 3D optical tomography capabilities combined in a single system, the IVIS Spectrum 2 is our next generation in optical imaging. This advanced imaging system incorporates a CCD camera with eXcelon® coating that enables detection of more signal at higher efficiency across a broader spectrum of wavelengths. With exclusivity to this innovative camera for in vivo imaging, the IVIS Spectrum 2 preclinical optical imaging system delivers the sensitivity you demand for non-invasive longitudinal imaging to better understand early disease-related biological changes, track disease progression, and help guide the drug development process.
Additional product information
Features and benefits
High sensitivity
Exclusivity to patented CCD camera with eXcelon coating for high sensitivity imaging
Rapid imaging
Fast data acquisition allows quick visualization of images in real-time
High throughput
Standard 5 mice configuration or up to 10 mice capacity using optional manifold
Trans-illumination
Imaging below the specimen for sensitive detection and quantification of deep fluorescent sources
Epi-illumination
Imaging above the specimen ideal for high throughput workflow
Co-registration
Seamless co-registration of optical data with other modalities, e.g., CT, MRI, SPECT, PET, Ultrasound
Spectral unmixing
Remove autofluorescence & easily identify, separate, and quantify multiplexed fluorescent signals
Analysis software
Broadly adopted, easy to use, and intuitive, Living Image® visualization and analysis software
High-performance CCD camera
The camera and coating facilitate detection of more signal at higher efficiency across a broader spectrum of wavelengths throughout the visible and NIR spectrum - giving you:
- Improved signal-to-noise ratio for both bioluminescent and fluorescent signals
- Increased bandwidth to encompass a wider range of NIR fluorescent probes
Camera highlights
- Patented eXcelon® coating
- Back-illuminated, thermoelectrically cooled (-90°C) CCD
- High quantum efficiency (peak >95%)
- 2048 x 2048 imaging pixels with 13.5 micron pixel size
- Low read noise
Bring your in vivo images to life with Living Image software
Broadly adopted imaging software that sets the industry standard for ease of use and flexibility
- Comprehensive set of tools for 2D and 3D data analysis
- One click 3D reconstructions
- Spectral unmixing algorithms to easily obtain and separate simultaneous fluorescent readouts or remove unwanted autofluorescence
- Co-register optical imaging with other modalities (e.g., CT, MRI, SPECT, PET)
- Auto settings for easy image acquisition
- Batch processing analysis tools
- Generation of animated movies and publication ready figures
- Flexible remote review for convenient offline analysis of data sets
- Included in IVIS purchase
Which IVIS system is best for your research?
| IVIS spectrum 2 | IVIS spectrumCT 2 | IVIS lumina S5 | IVIS lumina X5 | IVIS lumina III | IVIS lumina LT | IVIS lumina XRMS | |
|---|---|---|---|---|---|---|---|
| Capacity | Up to 10 mice* | Up to 10 mice* | Up to 10 mice* | Up to 10 mice* | Up to 5 mice** | Up to 5 mice** | Up to mice |
| Benchtop format | ✔ | ✔ | ✔ | ✔ | ✔ | ||
| 2D Bioluminescence / Fluorescence | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ | ✔/✔ |
| 3D Bioluminescence / Fluorescence | ✔/✔ | ✔/✔ | |||||
| Enhanced Fluorescence capabilities | ✔ | ✔ | ✔ | ✔ | ✔ | ✔ | |
| Integrated standard x-ray | ✔ | ||||||
| Integrated high resolution x-ray | ✔ | ||||||
| Integrated CT | ✔ | ||||||
| Optical FOV (cm) (Nominal) | 4-22.5 | 4-22.5 | 10-22.5 | 10-22.5 | 5-12(2.6**) | 5-12(2.6**) | 5-12 |
| Wavelength range (nm) | 415-850 | 415-850 | 410-865 | 410-865 | 410-865 | 415-875 | 410-865 |
| For additional comparison information please refer to the IVIS Comparison flyer under the ‘Resources’ tab *Using optional manifold kit **Using expansion lens |
|||||||
Specifications
| Height |
206.0 cm
|
|---|---|
| Portable |
No
|
| Width |
65.0 cm
|
| Brand |
IVIS
|
|---|---|
| Imaging Modality |
Optical Imaging
|
| Optical Imaging Classification |
Bioluminescence Imaging
Fluorescence Imaging
|
Video gallery
Resources
Case Study
A novel mouse model using optical imaging to detect on-target, off-tumor CAR-T cell toxicity
CAR-T therapy has achieved tremendous success in treating blood malignancies, however treating solid tumors with this therapy has...
Literature - Publication Review
Applications of In Vivo bioluminescence imaging for SARS-CoV-2
Scientists continue to explore several options to treat SARS-CoV-2 infection with hundreds of therapeutics at various phases of...
Brochure
Biologics workflow solutions
Precision biologics are playing an increasingly powerful role as part of therapeutic strategies such as monoclonal antibodies...
Literature - Publication Review
Biopolymers Codelivering Engineered T Cells and STING Agonists can Eliminate Heterogenous Tumors
Adoptive cell transfer using chimeric antigen receptor (CAR-T) cell therapy in which the patient’s T-cells are extracted...
Literature - Publication Review
Evaluating a novel nanoparticle platform for controlled liraglutide release in a Type II diabetes mouse model
A large percentage of Type 2 diabetes mortality is related to cardiovascular complications. Consequently, there is a critical need...
Application Note
Imaging oncolytic virus infection in cancer cells
Aside from the traditional small-molecule chemotherapeutics or targeted therapy agents that have been widely used in the clinic...
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