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EnVision XCite Multimode Plate Reader

Knowledge base

The EnVision™ XCite multimode plate reader provides exceptional sensitivity across all detection technologies, while keeping you flexible with both filter and monochromator based options plus full upgradeability.

And, the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP).

For research use only. Not for use in diagnostic procedures.

Part #: 2105-0020

Unit Size:

1 unit

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Product variant

1 unit

Unit Size: 1 unit

Part #: 2105-0020

Request information

Product information

Overview

Winner of SelectScience® Seal of Quality

Seals of Quality recognize the top 0.1% of laboratory products that consistently receive the highest customer review ratings and are designed to further assist scientists worldwide in making important purchasing decisions for their labs.

The EnVision XCite provides exceptional sensitivity and speed with minimal downtime – backed by our global network of application scientists and engineers.

Technologies included

Filter based fluorescence intensity (top and bottom)
Time-resolved fluorescence (top and bottom)
Luminescence, including glow, flash and dual luminescence
Filter-based absorbance
Fluorescence polarization

Optional technologies

Standard Alpha technology
High-throughput Alpha technology
Monochromator-based fluorescence intensity
Monochromator-based absorbance detection
Laser-based time-resolved fluorescence
Ultra-sensitive luminescence

Key Features

Field upgradeable for changing application needs
User-changeable, label-specific optical mirror modules and filters for assay customization with positive identification of measurement configuration (barcodes)
Maximum flexibility with optional quad monochromator

See full list of filters under the Resources.

Options:

2 channel dispenser
Plate stacker (20 or 50 plates)
Temperature control up to 55ºC
Compatible with a wide range of automation systems
Signals VitroVivo for multimode detection (MMD) is tailored to the analysis of plate reader data and enables you to visualize, correlate, compare and analyze your data and share freely with your colleagues
Integrated barcode reading enables barcode reading from short right side and both long sides of the plate
Optional 21 CFR Part 11 support

Outstanding Support

We understand your science and applications - with our years of experience developing and supporting multimode plate readers and reagents. And with support from our global network of application scientists and engineers, you can be confident of minimal downtime.

Part of a Total Solution for Screening

EnVision is part of our complete solution for screening. For high-throughput screening, we offer assays and reagents, radioimmunoassays and radiometric detection, microplates and automation, in addition to multimode plate readers. We also offer solutions for phenotypic screening such as high-content screening systems and for data analysis such as Signals™ Image Artist

Specifications

Other specifications

21CFR Compatible	Yes
Automation Compatible	Yes
Brand	EnVision
Detection Modality	Absorbance Alpha Fluorescence Fluorescence Polarization Luminescence Time-Resolved Fluorescence (TRF)
Model	EnVision XCite
Unit Size	1 unit

Image gallery

Spectra viewer

The Spectra Viewer tool helps you visualize the spectral compatibility of fluorophores and fluorescent labelled probes so you can determine what filters are best for detection. Choose the appropriate Revvity multimode plate reader from the Select Machine drop-down menu. After selection, filters for the chosen instrument will be displayed automatically.

References

The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Omi, J., Watanabe-Takahashi, M., Igai, K. et al. Nat Commun 11, 162 (2020). https://doi.org/10.1038/s41467-019-13974-w
A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Wei Shi, Han-Qing Ye, Cheng-Lin Deng, Rui Li, Bo Zhang, Peng Gong. Nucleic Acids Research, Volume 48, Issue 3, 20 February 2020, Pages 1392–1405. https://doi.org/10.1093/nar/gkz1170
Structure of M^pro from COVID-19 virus and discovery of its inhibitors. Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng et al. bioRxiv 2020.02.26.964882; https://doi.org/10.1101/2020.02.26.964882
Anthralin Suppresses the Proliferation of Influenza Virus by Inhibiting the Cap-Binding and Endonuclease Activity of Viral RNA Polymerase. Hu Ao, Li Jing, Tang Wei, Liu Ge et al. Frontiers in Microbiology, Volume 11 (2020), Pages 178. https://doi.org/10.3389/fmicb.2020.00178
Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis. Zhihui Jia, Liming Yan, Zhilin Ren, Lijie Wu et al. Nucleic Acids Research, Volume 47, Issue 12, 09 July 2019, Pages 6538–6550, https://doi.org/10.1093/nar/gkz409
Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999-2007 in Taiwan. Wang Y-F, Chang C-F, Tsai H-P, Chi C-Y, Su I-J, Wang J-R. PLoS ONE (2018), 13(5): e0196727. https://doi.org/10.1371/journal.pone.0196727
Antibody profiles to wheat germ cell-free system synthesized Plasmodium falciparum proteins correlate with protection from symptomatic malaria in Uganda. Kanoi, Bernard N et al. Vaccine (2017), 35(6): 873-881. https://doi.org/10.1016/j.vaccine.2017.01.001
Novel Small Molecule Entry Inhibitors of Ebola Virus. Basu, Arnab et al. The Journal of Infectious Diseases (2016), 212 Suppl 2:S425-34. https://doi.org/10.1093/infdis/jiv223
A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein. Landeck, Natalie et al. Molecular Neurodegeneration (2016), 11(1):61. https://doi.org/10.1186/s13024-016-0125-0
Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell lysates: application to screening of new anti-malarials. Mata-Cantero, Lydia et al. Malaria Journal (2015), 14:200. https://doi.org/10.1186/s12936-015-0708-1