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Application Note
Complex genome engineering with the Pin-point base editing system
When performing gene editing using CRISPR-Cas systems, the double strand DNA breaks introduced can be cytotoxic, particularly in sensitive cell types. These cytotoxic effects are amplified when multiple target sites are edited at the same time because the cell must repair multiple breaks to the genome.
Read this application note to find out how the Pin-point™ base editing platform can be applied to complex gene editing, even in sensitive cell types.
Pin-point™ base editing reagents are available for research use only and are not for diagnostic use or direct administration into humans or animals. The Pin-point™ base editing platform technology is available for clinical or diagnostic study and commercialization under a commercial license from Revvity.
For research use only. Not for use in diagnostic procedures.
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Complex genome engineering with the Pin-point base editing system