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    • Academia
      Explore BioLegend

      Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

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    • Pharma / Biotech
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  • Products
    • Research & Development
      • Genomic Analysis
        • IncRNA in Functional Studies
        • Nucleic Acid Isolation
        • NGS Workflows
        • Microplate Readers
        • Microfluidic Nucleic Acid Analysis
        • CRISPR Technologies
        • RNA Interference
        • Transfection and Ancillary Reagents
        • Oligonucleotide Custom Synthesis
        • cDNAs and ORF Clones
        • Single-Cell Sequencing
        • Labeled Nucleotides
        • qPCR
        • Library Prep Kits
        • Magnetic Beads
        • Viral Vector Products
        25% OFF select new reagents

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      • Protein Analysis
        • Binding Assays
        • Immunoassays
        • Microfluidic Protein Characterization
        • Microplate Readers
        • Microplates
        • Recombinant Proteins
        • Western Blotting
        • Sample Dissociation
        • M-PVA Magnetic Beads
        25% OFF select new reagents

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      • Cell Analysis
        • Cell Isolation
        • Cell Lines & Stem Cells
        • Cell Counting and Image Cytometry
        • Cell Health & Viability
        • Cellular Imaging & Analysis
        • Immunoassays
        • In Vivo Imaging
        • Microplates
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      • Research Solutions
        • Bioprocessing
        • Agrigenomics Workflows
        • Assay Development Workflows
        • Biobanking Workflows
        • Biologics
        • Biomarker Discovery
        • Cell and Gene Therapy
        • Disease Research
        • Drug Development
        • Functional Genomic Screening Solutions
        • GMP Workflows
        • Immunoassays Solutions
        • Microphysiological Systems
        • pHSense Reagents
        • Precision Medicine Research
        • Small Molecule Drug Discovery
        • Target Class
        25% OFF select new reagents

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      25% OFF select new reagents

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    • Clinical & Diagnostics
      • Reproductive Health
        • Maternal and Prenatal Testing
        • Reproductive Health Data Management
        • Revvity Genomics Software
        • Newborn Screening
        • Newborn Sequencing Research
        • Pregnancy-Relevant Infections
        • Endocrine Reproductive
        • Cell-free DNA Analysis
        • Neonatal Research
        • Preimplantation Genetic Testing
        • PlGF Testing Research
        • Molecular Cytogenetics
        New IVD Mimix™ reference standards for oncology workflows.

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      • Infectious Diseases
        • Tuberculosis Management
        • EUROIMMUN Solutions
        • IDS Solutions
        • Nucleic Acid Isolation for Pathogen Detection
        • Cytomegalovirus
        • SARS-COV-2 Testing Solutions
        • Bacterial & Viral Nucleic Acid Isolation
        • Metagenomics
        New IVD Mimix™ reference standards for oncology workflows.

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      • Cancer
        • ASR Flow Cytometry Antibodies
        • HPV Testing
        • ctDNA Workflows
        • miRNA-seq Analysis
        • Exosome/cfRNA Analysis
        • Targeted Sequencing
        • Mimix Reference Standards
        • Functional Testing
        NEW! Mimix IVD reference standards

        Providing diagnostic labs with trusted quality controls for developing tests and monitoring workflows, with the added assurance of IVD marking. Explore our newest MimixTM controls.

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      • Autoimmunity
        • EUROIMMUN Solutions
        • IDS Solutions
        New IVD Mimix™ reference standards for oncology workflows.

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      • Endocrinology
        New IVD Mimix™ reference standards for oncology workflows.

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      • Allergy
        New IVD Mimix™ reference standards for oncology workflows.

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      • Neurodegeneration
        • Alzheimer's Disease
        • Amytrophic Lateral Sclerosis (ALS)
        • Neurogranin
        • BACE1
        New IVD Mimix™ reference standards for oncology workflows.

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      • Rapid Patient Testing
        New IVD Mimix™ reference standards for oncology workflows.

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      New IVD Mimix™ reference standards for oncology workflows.

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    • Reagents
      • BioLegend
        25% OFF select new reagents

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      • Cellular Imaging Reagents
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      • chemagic Nucleic Acid Purification Kits
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      • CRISPR Technologies
        Save 30% off Dharmacon™ CRISPR and RNAi screening libraries

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      • GPCR Research Reagents
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      • Immunoassays
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      • In Vivo Imaging Reagents
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      • Liquid Scintillation Cocktails
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      • NGS Library Prep Kits
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      • pHSense Reagents
        25% OFF select new reagents

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      • qPCR
        25% OFF select new reagents

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      • Radiochemicals
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      • RNA Interference
        Save 30% off Dharmacon™ CRISPR and RNAi screening libraries

        Use promocode SAVENOW30. Sale expires November 22

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      • Primary and Secondary Antibodies
        25% OFF select new reagents

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      25% OFF select new reagents

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    • Platforms & Automation
      • Nucleic Acid Purification
        • chemagic Applications
        • chemagic IVD Instruments
        • chemagic IVD Kits
        • chemagic Instruments
        • chemagic Kits
        • M-PVA Magnetic Beads
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Automated Liquid Handling
        • Flow Cytometry Cocktail Prep Automation
        • Liquid Handling Workstations
        • Automated Liquid Handling Applications
        • Liquid Handling Consumables & Accessories
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Integrated Lab Automation
        • Automated Plate Loading
        • Workstation Modules
        • Scheduling & Control Software
        • Robotics
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Microfluidic Analysis
        • Microfluidic Protein Characterization
        • Microfluidic Nucleic Acid Analysis
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Detection Solutions
        • Plate Reader Accessories
        • Microplate Readers
        • Radiometric Detectors
        • Radiochemicals
        • Liquid Scintillation Cocktails
        • Radiometric Consumables & Accessories
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Imaging
        • Cellular Imaging & Analysis
        • In Vivo Imaging
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Cell Counting and Image Cytometry
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Sample Homogenization
        • Homogenizers
        • Homogenizer Accessories
        • Homogenizer Consumables
        • Sample Centrifugation
        • Sample Sonication
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • In Vitro Diagnostics (IVD) Platforms & Automation
        • IVD Nucleic Acid Isolation
        • IVD Automated Liquid Handling
        • IVD Radiometric Detectors
        • EUROIMMUN Instruments
        • IDS Instruments
        • Clinical Applications
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Consumables & Accessories
        • Cassettes
        • Cell Harvesters
        • In Vivo Imaging Accessories
        • Microplates
        • Radioactive Spill Cleaners
        • Scintillation Cocktails
        • Transfer Membranes
        • Charcoal Traps
        • Homogenizer Accessories
        • Homogenizer Consumables
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Instrument Service & Maintenance
        • On Demand Equipment Service
        • Equipment Service Plans
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      New! Cellometer™ Ascend™

      Explore our cell counting and image cytometry solutions.

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    • Consumables & Accessories
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    • Signals Software
      • All Products
        • Signals One
        • ChemDraw
        • Spotfire®
        • Signals Clinical
        • Signals Notebook
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      • All Solutions
        • Biology
        • Discovery Chemistry
        • Clinical & Translational
        • Specialty Chemicals
        • Food/Flavor/Fragrance
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    • Revvity Omics Services
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  • Services
    • Preclinical Services
      • Antibody Drug Conjugate Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Complex Cell Model Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Base Editing Platform
        • Pin-point base editing platform cell line engineering services
        • Pin-point base editing platform pooled tiled screening services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Immune Cell Screening
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Functional Genomic Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Cell Panel Screening
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Cell Line Engineering
        • CHOSOURCE CLE Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Viral Vector Engineering and Manufacture
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      Preclinical services

      Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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    • Revvity Omics Services
      • Revvity Omics Clinical Services
        • Cytogenomics
        • Global Laboratory Network
        • Metabolic Testing
        • Newborn Screening Services
        • Prenatal Screening Services
        • Proactive Testing
        • Rare Disease Testing
        • Specialized and Customized Assays
        • Sponsored Testing Programs
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Clinical & Testing Services
      • ViaCord Cord Blood & Cord Tissue Banking
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Clinical Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Cellular and Humoral Immunoassays
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Tuberculosis Testing Services
        • Oxford Diagnostic Laboratories Service Closures
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customization Services
      • Assays and Reagents
        • Assay Development
        • Compound profiling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Microplate Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Custom Conjugation & Labeling
        • Custom Labeling
        • Small Molecule
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Radiosynthesis and Labeling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Licensing
      • Gene Delivery Licensing
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Gene Expression Systems
        • AAV Production Platform
        • CHOSOURCE Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Pin-point™ Base Editing Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Virus Screening
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      CHOSOURCE expression platform

      Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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    • Viral Vector Engineering and Manufacture
      • AAV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Lentivirus Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

        Learn more

      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Instrument Service & Maintenance
      • AV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Equipment Service Plans
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • On-demand Equipment Service
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

        Learn more

      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customer Training
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • OEM Solutions
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    T-SPOT.TB testing services.

    Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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  • Company
    • About Us
      • Purpose
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      • Approach
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      • Stories
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      • Leadership
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    • Careers
      • Careers Home
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      • Why Revvity
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      • Search Jobs
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    • Investor Relations
      • Events
        Investor Day 2024

        Driving meaningful innovation that profoundly impacts science and human lives.

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        Investor Day 2024

        Driving meaningful innovation that profoundly impacts science and human lives.

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      • Stock Info
        Investor Day 2024

        Driving meaningful innovation that profoundly impacts science and human lives.

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      Investor Day 2024

      Driving meaningful innovation that profoundly impacts science and human lives.

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    • ESG
      • Environmental
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      • Governance
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    • News
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      • Press Coverage
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  • Resources
    • Product Support
      • Application Support Knowledge base (ASK)
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  • Brands
      Revvity Brands
    • BioLegend

    • EUROIMMUN

    • Revvity Omics

    • Revvity Signals

    • Tulip Diagnostics

    • ViaCord

    • Popular Revvity Product Brands
    • AlphaLISA and SureFire Ultra

    • BioQule NGS

    • chemagic

    • EnVision Nexus

    • Fontus

    • HTRF

    • IVIS

    • LEGENDplex

    • Opera Phenix

    • T-SPOT

    • TotalSeq

    • View all Revvity brands
  • Welcome to Revvity: renowned brands and boundless innovation.

    Hearing the word "can't" is our call to action!

    We help scientists, researchers, and clinicians overcome the world's greatest health obstacles.

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    Featured brand: BioLegend

    Learn about our world-class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

    Visit BioLegend.com

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Preclinical Services

Accelerating your research from discovery through therapeutic development

In the fast-paced world of therapeutic discovery, using resources efficiently to drive rapid and accurate decision-making is essential. Partner with experts to overcome challenges and alleviate obstacles such as knowledge gaps or resource availability.
 

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Actionable data you can trust

At Revvity, we provide a suite of preclinical CRO services to biotechnology and pharmaceutical clients worldwide to help accelerate the drug discovery journey. 

Diagram showing the scope of Revvity Preclinical Services across stages of drug discovery and development

“We included data generated by Revvity as part of this Nature publication because they have consistently provided high quality, actionable data that we trust.”
 

Dr. Philipp Jaeger, Director of High-Throughput Biology at Boehringer Ingelheim, Vienna

Kim, D. et al. Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature 619, 160–166 (2023).

Our preclinical contract research organization (CRO) services include industry-leading cell-based screening solutions based on deep experience and knowledge. Revvity has the expertise and resources to support your cell model design and preclinical screening needs for various modalities, from target ID to therapeutic asset validation studies across the preclinical drug discovery process.

Focus on your core priorities by outsourcing to our experienced scientific team and leveraging our advanced technologies.

Partner with us to understand how your therapeutic works, what impacts its efficacy and determine in-vitro, predictive biomarkers and oncology indications with the best potential outcome.

Get reliable data to support you in making the right models and decisions.

Experience across modalities, including small molecules, biologics, oligo-based therapeutics, and more.

Coverage of preclinical applications, including target identification, target validation, mechanism of action studies, drug-gene interaction studies, and more.

Experience the power of Revvity's experienced scientists and advanced technologies

By working with our preclinical services team, you can benefit from the know-how of our experienced scientists and our advanced platforms, such as Pin-point™ base editing technology, OncoSignature™ and ImmuSignature™ compound screening. We expand the possibilities by exploring a variety of readouts, including high content imaging, HTRF™, AlphaLISA™ and LEGENDplex™ assays, to generate reliable data you can trust to help you make the right decisions.

Quality cell engineering and screening solutions for preclinical oncology drug discovery

For nearly two decades, our team has delivered quality preclinical oncology services, specializing in oncology assays and high-throughput screening, for clients worldwide. Our platforms are trusted by top pharmaceutical companies for outsourcing oncology cell-based screening and cell engineering. With extensive expertise and advanced technology, we provide reliable preclinical oncology services and tailored solutions that help accelerate drug discovery in oncology and immuno-oncology research.

Viral vector development expertise

In the space of cell and gene therapy, our gene delivery team, where SIRION Biotech’s expertise lives on, can partner with you to help advance your viral vector development and manufacturing. Leveraging many years of experience, cutting-edge technology, and an extensive GMP network, we can help you to expedite your therapy's journey to market success.

Choose the right model for outsourcing preclinical services

We understand that every drug discovery project has unique requirements, which is why we offer three tiers of model to meet your specific needs. Whether you're looking for speed and well-tested results, to answer unmet questions in the industry, or to expand the frontier of science, we’ve got you covered.

Tier One preclinical services: reproducible, cost-effective standard assays

TIER ONE

Reproducible and cost-effective standard assays

  • Standard KO and KI cell model generation
  • OncoSignature Assays
  • ImmuSignature Assays
  • Pooled CRISPR Standard Drug-gene interaction
  • Pooled CRISPR Standard Gene-gene interaction
  • Pre-determined configuration options
Tier Two preclinical services: customized projects and expanded capabilities

TIER TWO

Custom projects and capabilities 

  • Pooled phenotypic and scCRISPR screens
  • T cell CRISPRko arrayed and pooled screening
  • Immune cell co-culture and complex model screens
  • Cell panel screens with custom read-outs such as HTRF or imaging
  • Expanded customization and assay configuration
Tier Three preclinical services: Fee for development bespoke projects

TIER THREE

Fee for development bespoke projects

  • Other primary cell types with differentiation protocols
  • Work with base editing or novel editing paradigms
  • Substantial R&D for assay development
  • Flexible experimental plan based on results
  • Projects based on quarterly workload 

Not sure which model fits your project? Contact us today to discuss how our preclinical CRO services can support your therapeutic preclinical discovery and development process and the best solution for your needs.

Explore our preclinical services

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Immune Cell Screening

Preclinical screening services using primary human immune cells to address biologically relevant questions for target identification and lead optimization.

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Functional Genomic Screening

Identify and characterize drug discovery targets with functional genomic screening services. Offering CRISPR knockout, CRISPR activation, CRISPR inhibition, dual screening and RNAi technologies.

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Cell Panel Screening

Identify cells that respond to therapeutics by screening over 300 standard cancer cell lines in 2D or 3D formats using OncoSignature screening services.

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Cell Line Engineering

Project updates are provided at regular intervals with validation and QC performed throughout prior to shipping the final clone and parental line alongside the full data pack.

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Base Editing Platform

Advance therapeutic research with precise, efficient multiple gene editing through our novel Pin-point base editing services.

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Antibody Drug Conjugate Services

In the discovery of oncology therapeutics, Antibody-drug conjugates (ADCs) are rapidly gaining momentum, with hundreds of candidates advancing through clinical development.

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Viral Vector Engineering and Manufacture

Individualized and customized solutions tailored to fit viral vector projects at all stages of discovery and development, ensuring fast and cost-effective product manufacture. 

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Complex Cell Model Screening Services

Traditional 2D cell models fail to capture the complexity of human biology in today’s dynamic research environment. 

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Featured resources

eBook

Cell engineering and screening services

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Application Note

Machine-learning prediction of drug mechanism of action from high-content cell painting images

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How can we help you?

We are here to answer your questions.

Contact our services team
Contact our services team
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