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    • Academia
      Explore BioLegend

      Learn about our world class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

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  • Products
    • Research & Development
      • Genomic Analysis
        • IncRNA in Functional Studies
        • Nucleic Acid Isolation
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        • Microplate Readers
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        • CRISPR Technologies
        • RNA Interference
        • Transfection and Ancillary Reagents
        • Oligonucleotide Custom Synthesis
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        • Viral Vector Products
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      • Protein Analysis
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        • Sample Dissociation
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      • Cell Analysis
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      • Research Solutions
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        • Biologics
        • Small Molecule Drug Discovery
        • Disease Research
        • Target Class
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        • Functional Genomic Screening Solutions
        • Assay Development Workflows
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    • Clinical & Diagnostics
      • Reproductive Health
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        • Pregnancy-Relevant Infections
        • Endocrine Reproductive
        • Cell-free DNA Analysis
        • Neonatal Research
        • Preimplantation Genetic Testing
        • PlGF Testing Research
        • Molecular Cytogenetics
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      • Infectious Diseases
        • Tuberculosis Management
        • EUROIMMUN Solutions
        • IDS Solutions
        • Nucleic Acid Isolation for Pathogen Detection
        • Cytomegalovirus
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        • Bacterial & Viral Nucleic Acid Isolation
        • Metagenomics
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      • Cancer
        • ASR Flow Cytometry Antibodies
        • HPV Testing
        • ctDNA Workflows
        • miRNA-seq Analysis
        • Exosome/cfRNA Analysis
        • Targeted Sequencing
        • Mimix Reference Standards
        • Functional Testing
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        Providing diagnostic labs with trusted quality controls for developing tests and monitoring workflows, with the added assurance of IVD marking. Explore our newest MimixTM controls.

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      • Autoimmunity
        • EUROIMMUN Solutions
        • IDS Solutions
        New IVD Mimix™ reference standards for oncology workflows.

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      • Endocrinology
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      • Allergy
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      • Neurodegeneration
        • Alzheimer's Disease
        • Amytrophic Lateral Sclerosis (ALS)
        • Neurogranin
        • BACE1
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      • Rapid Patient Testing
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      New IVD Mimix™ reference standards for oncology workflows.

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    • Reagents
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      • chemagic Nucleic Acid Purification Kits
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      • CRISPR Technologies
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    • Platforms & Automation
      • Nucleic Acid Purification
        • chemagic Applications
        • chemagic IVD Instruments
        • chemagic IVD Kits
        • chemagic Instruments
        • chemagic Kits
        • M-PVA Magnetic Beads
        New! Cellometer™ Ascend™

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      • Automated Liquid Handling
        • Flow Cytometry Cocktail Prep Automation
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        • Automated Liquid Handling Applications
        • Liquid Handling Consumables & Accessories
        New! Cellometer™ Ascend™

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      • Integrated Lab Automation
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        • Robotics
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Microfluidic Analysis
        • Microfluidic Protein Characterization
        • Microfluidic Nucleic Acid Analysis
        New! Cellometer™ Ascend™

        Explore our cell counting and image cytometry solutions.

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      • Detection Solutions
        • Plate Reader Accessories
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        • Radiometric Detectors
        • Radiochemicals
        • Liquid Scintillation Cocktails
        • Radiometric Consumables & Accessories
        New! Cellometer™ Ascend™

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      • Imaging
        • Cellular Imaging & Analysis
        • In Vivo Imaging
        New! Cellometer™ Ascend™

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      • Cell Counting and Image Cytometry
        New! Cellometer™ Ascend™

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      • Sample Homogenization
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        • Sample Centrifugation
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        New! Cellometer™ Ascend™

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      • In Vitro Diagnostics (IVD) Platforms & Automation
        • IVD Nucleic Acid Isolation
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        • EUROIMMUN Instruments
        • IDS Instruments
        • Clinical Applications
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      • Consumables & Accessories
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        New! Cellometer™ Ascend™

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      • Instrument Service & Maintenance
        • On Demand Equipment Service
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      New! Cellometer™ Ascend™

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    • Consumables & Accessories
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    • Signals Software
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      • All Solutions
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  • Services
    • Preclinical Services
      • Antibody Drug Conjugate Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Complex Cell Model Screening Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Base Editing Platform
        • Pin-point base editing platform cell line engineering services
        • Pin-point base editing platform pooled tiled screening services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Immune Cell Screening
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      • Functional Genomic Screening Services
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      • Cell Panel Screening
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      • Cell Line Engineering
        • CHOSOURCE CLE Services
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      • Viral Vector Engineering and Manufacture
        Preclinical services

        Work with our experienced scientific team and leverage our advanced technologies to help accelerate the preclinical drug discovery process.

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      Preclinical services

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    • Revvity Omics Services
      • Revvity Omics Clinical Services
        • Cytogenomics
        • Global Laboratory Network
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        • Specialized and Customized Assays
        • Sponsored Testing Programs
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Clinical & Testing Services
      • Revvity Omics Clinical Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Revvity Omics Pharma Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Cellular and Humoral Immunoassays
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Tuberculosis Testing Services
        • Oxford Diagnostic Laboratories Service Closures
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customization Services
      • Assays and Reagents
        • Assay Development
        • Compound profiling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Microplate Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Custom Conjugation & Labeling
        • Custom Labeling
        • Small Molecule
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Radiosynthesis and Labeling
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Licensing
      • Gene Delivery Licensing
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Gene Expression Systems
        • CHOSOURCE Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Pin-point™ Base Editing Platform
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      • Virus Screening
        CHOSOURCE expression platform

        Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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      CHOSOURCE expression platform

      Revvity's expression platform provides an enhanced system for the development and manufacturing of biotherapeutics that can be used in commercial manufacturing applications.

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    • Viral Vector Engineering and Manufacture
      • AAV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Lentivirus Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Instrument Service & Maintenance
      • AV Services
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • Equipment Service Plans
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      • On-demand Equipment Service
        T-SPOT.TB testing services.

        Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • Customer Training
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    • OEM Solutions
      T-SPOT.TB testing services.

      Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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    T-SPOT.TB testing services.

    Revvity's Oxford Diagnostic Laboratories is a large referral laboratory for tuberculosis testing services based on our T-SPOT technology.

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  • Company
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    • Investor Relations
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        Investor Day 2024

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      Investor Day 2024

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  • Brands
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    • BioLegend

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    • Popular Revvity Product Brands
    • AlphaLISA and SureFire Ultra

    • BioQule NGS

    • chemagic

    • EnVision Nexus

    • Fontus

    • HTRF

    • IVIS

    • LEGENDplex

    • Opera Phenix

    • T-SPOT

    • TotalSeq

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  • Welcome to Revvity: renowned brands and boundless innovation.

    Hearing the word "can't" is our call to action!

    We help scientists, researchers, and clinicians overcome the world's greatest health obstacles.

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    Featured brand: BioLegend

    Learn about our world-class antibodies for a diverse set of research areas including immunology, neuroscience, cancer, stem cells and cell biology.

    Visit BioLegend.com

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Microphysiological System Solutions

Enhance the relevance of your research

Drug discovery endeavors require a deep understanding of biological systems and their response to potential therapeutics. That’s where microphysiological systems (MPS) play a pivotal role. They offer a more accurate representation of cellular biology that goes beyond traditional approaches, enabling researchers to understand disease mechanisms and find new treatments that translate into clinical response.

If you are working on your next 3D cell model project, and trying to select the right culture method, genetically modify your cells, automate your workflow, or analyze your samples and data, at Revvity we have microphysiological system solutions to partner with you with the purpose of reaching your goals. Together, we can redefine what’s possible by developing innovative treatments and precise therapeutic solutions to improve human health and lives around the world.
 

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Animal modelsStem cell and iPSC-derived disease modelsOrgan-on-chipBioprinted modelsSpheroids and organoids
Physiological model solutions benefits interactive imageThis SVG depicts various shapes and models related to spheroids and organoids in biological studies, including representations of animal models and stem cell-derived disease models.Animal modelsStem cell and iPSC-derived disease modelsOrgan-on-chipBioprinted modelsSpheroids and organoids

Bioprinted models

Description

Allows research to form hydrogels with properties matching various tissue types and physiologically relevant matrix environments.

Benefits

  • High reproducibility
  • High throughput
  • Suitable for HTS

Organ-on-chip

Description

Microfluidic cell culture devices lined with living cells cultured under fluid flow.

Benefits

  • Recapitulates human organ function and disease pathophysiology
  • Assess the safety and efficacy of drug candidates in humans with greater precision

Animal models

Description

Widely used models to track, monitor and visualize disease processes.

Benefits

  • Evaluate effectiveness or toxicity of drug candidates
  • Xenograft models (PDX) enable tumor growth monitoring

Spheroids and organoids

Description

3D clusters of cells or mini-organs that are more physiological relevant than traditional 2D cultures.

Benefits

  • Mimic cell-to-cell interactions and the microenvironnement
  • Composed of different cell types of the original tissue

Stem cell and iPSC-derived disease models

Description

Stem cells propagate indefinitely and can give rise to every other cell type in the body.

Benefits

  • Models from healthy or diseased donors
  • Study disease phenotypes at the cellular level


For research use only. Not for use in diagnostic procedures.

img-organoid-derived872x872
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    Culture Treatment Model Analysis Data Analysis Services
    Culture

    When it comes to developing advanced physiological models — it’s critical to select the cell model with the right genomic context and biological function to recapitulate a healthy or diseased phenotype.

    Achieving this level of accuracy requires tightly controlled culture conditions and reliable cell counting for cell seeding. Choosing a 2D or 3D cell culture method depends on the biological question, complexity of the desired model, and readout technology. Cells can be grown as monolayers, single spheroids in ultra-low attachment (ULA) plates, or cultured in hydrogels, offering a variety of options to enhance your research capabilities. Count on us to expertly scale up these methods, utilizing liquid handling techniques.

    Featured products:
    microplates-512
    Microplates

    Choosing the right microplate is a critical, often overlooked, part of an assay. The right microplate helps provides valuable data, whereas the wrong microplate can lead to missed or inaccurate data leading to missed project timelines and ultimately higher costs.

    Learn more
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    Fontus Workstations

    With easy-to-use software, optimized deck access, verified protocols, and reformatting capabilities to simplify your workflows and improve turnaround times

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    Cell Counting & Image Cytometry Instruments

    Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

    Learn more
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    Viral Vector Products

    Viral vectors are the most efficient vehicles for gene delivery into a specific cell type or tissue for a wide array of research purposes.

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    Recombinant Proteins

    Our portfolio includes over 2,000 bioactive human, mouse, and rat recombinant proteins developed in-house.

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    crispr technologies
    CRISPR Technologies

    CRISPR-Cas9 genome engineering technologies hold great promise for understanding diseases and for the development of life saving treatments.

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    Treatment

    In modern drug discovery, multiple screening methods play a vital role in identifying potential drug targets and eventual drug candidates. Traditionally, small molecule libraries were screened for compounds acting on a known molecule or for a desired biological effect. However, a drug candidate is only as good as its target.

    To ensure the utmost precision, today’s drug discovery leverages gene editing or gene silencing methods such as CRISPR or siRNAs to identify suitable drug targets. Understanding the causal gene behind a phenotype or genes that contribute to a phenotype can significantly boost the confidence in a new drug candidate. Get ready to experience advancements in your research as we deliver convenience and efficiency.

    Featured products:
    Fontus Liquid Handling Workstation-Revvity-512x288
    Fontus Workstations

    With easy-to-use software, optimized deck access, verified protocols, and reformatting capabilities to simplify your workflows and improve turnaround times

    Learn more
    crispr technologies
    CRISPR Technologies

    CRISPR-Cas9 genome engineering technologies hold great promise for understanding diseases and for the development of life saving treatments.

    Learn more
    rna interference
    RNA Interference

    Dharmacon™ siRNA, shRNA, and microRNA-based reagents, leading the field for nearly 30 years providing highly specific and efficient gene silencing.

    Learn more
    Model Analysis

    Selecting the right method for measuring the biological response of 3D cell models depends on the specific research question and the characteristics of the model system in use.

    Whether you’re repeatedly monitoring microtissue size or measuring sensitive detection of secreted proteins, each readout type poses unique challenges that can be overcome with the right tools. Our microplate readers, high-content analysis systems, and innovative reagents are complemented by specially designed microplates. Together, they shine a light on your samples, offering powerful insights to propel your research forward.

    Featured products:
    LabChip GX Touch Nucleic Acid Analyzer
    LabChip GX Touch Nucleic Acid Analyzer

    Accurate sizing, quantification and quality control of DNA, RNA, and NGS libraries.

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    3d-cell-512x288
    3D Cell Model Imaging and Analysis

    Our high-content analysis systems and reagents provide sensitive solutions for 3D cell imaging, and our intuitive software platforms give you the tools to interrogate these complex models in detail

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    microplate readers
    Microplate Readers

    As many of you know, microplate readers are instruments used to detect biological, chemical, biochemical or physical events from samples in a microplate.

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    immunoassays
    Immunoassays

    Since their introduction in the 1950’s, immunoassays have been an integral part of research and drug discovery.

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    Luminescence assay_512x288
    Luminescence Assays

    Luciferase assays allow for the study of transcriptional gene expression, virus life cycles, and cell viability.

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    nucleic acid isolation
    Nucleic Acid Purification

    Revvity provides a unique and efficient method for isolating nucleic acids based on chemagic™ technology established over 25 years.

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    cellometer-ascend-automatic-cell-counter-512x288.png
    Cell Counting & Image Cytometry Instruments

    Revvity offers a leading portfolio of automated cell counters, image cytometry systems, and cell counting reagents and consumables. Together, they provide fast, accurate and efficient ways to assess cell health and viability.

    Learn more
    totalseq_512x288.jpg
    Multiomics and TotalSeq Reagents by BioLegend

    Multiomics provides unparalleled protein and genetic analysis. Explore how our TotalSeq™ reagents can be integrated into your existing workflows and expand your capabilities.

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    Integrated Lab Automation
    Integrated Lab Automation

    From cellular screening and imaging applications to high-throughput screening and genomics-based applications, custom explorer™ G3 integrated workstations

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    Data Analysis

    Extracting insights from complex 3D datasets is no easy task. It requires the meticulous analysis of readouts and vast amounts of information (in context). But no worries—we’ve got you covered.

    With our scientific software and informatics solutions, you gain the ultimate tools to optimize 3D cell model imaging. Seamlessly aggregate, search, mine, and visualize critical data, converting it into actionable insights that drive your research forward. We are here to help you meet the challenges of data analysis head on—so you can embark on a journey of ground-breaking discoveries.

    Featured products:
    Signals-Image-Artist-Cell-Painting-Analysis-700x700.jpg
    Signals Image Artist

    Signals Image Artist has powerful capabilities for processing, analyzing, storing, and sharing all your high-content screening and cell imaging data – so you can significantly cut your time to results.

    Learn more
    signals Research Suite
    Signals One

    Make your innovations a reality with the first unified, cloud-native SaaS R&D platform that streamlines scientific complexity and promotes collaboration.

    Learn more
    Services

    Discover how our complex cell model screening services can accelerate your drug discovery and development goals. Our team leverage Revvity’s advanced imaging technologies and an extensive library of spheroids and primary immune cells to provide more biologically relevant data. This allows for better prediction of human responses to therapeutic interventions in immuno-oncology.

    From assay design to high-throughput screening, we provide an end-to-end service that supports every phase of your drug development, with dedicated project management you can trust.

    Featured services:
    Infiltration-252x252
    Advanced 3D cell culture models services

    Our complex cell model screening services leverage Revvity’s advanced imaging technologies and an extensive library of spheroids and primary immune cells, providing more biologically relevant data.

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    Featured resources

    Publication review

    Advanced characterization tools for organoid research: Analyzing cell type diversity, morphology, and function

    Learn more

    eBook

    Upscaling organoid research for sharper biological insights

    Learn more

    Article

    Revolutionizing neurodegenerative disease research with brain-on-chip technology

    Learn more

    Publication review

    Unlocking the potential of cancer immunotherapy: Overcoming the challenges of 3D immune cell killing assays

    Learn more

    Video

    Partnering with Purpose: Collaboration with Australian Organoid Facility

    Learn more

    Publication review

    Revolutionizing neurodegenerative disease research with brain-on-chip technology

    Learn more

    eBook

    Upscaling organoid research for sharper biological insights

    Learn more

    Technical note

    Automated high-content assay using GrowDex-embedded spheroids dispensed on JANUS G3 automated liquid handling workstation

    Learn more

    Publication review

    Organ-on-chips- increased complexity for higher physiological relevance in pharmaceutical safety testing

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    Webinar

    Revolutionizing drug safety: tools reshaping toxicology

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    Infographic

    Deeper insights from your 3D cell model imaging

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    Infographic

    Why 3D: stripping complexity out of multi-dimensional cell models

    Learn more

    Application note

    Proliferation and cell death analyses of 3D cultures using Revvity CellCarrier Spheroid ULA microplates and ATPlite 3D products

    Learn more

    Technical note

    A scalable and reproducible workflow for high-content analysis of cytotoxic effects in RASTRUM 3D cell cultures

    Learn more
    View all resources View all resources

    Featured blogs

    organ1920x1080
    Rethinking Alzheimer’s disease with brain-on-chip technology.

    Explore how brain-on-chip models are advancing Alzheimer’s research by targeting toxic amyloid-beta oligomers in ETAP-Lab’s latest preclinical work.

    img-blog-organoid512x288
    Essential characterization techniques for organoid cell models.

    Advanced characterization tools play a pivotal role in standardizing organoid production, enabling more accurate disease modeling and drug screening

    aof-thumbail
    Partnering with purpose: collaboration with Australian Organoid Facility.

    Organoids are becoming increasingly popular advanced cell-based model systems globally.

    predictive512x288
    Revolutionizing drug safety: tools reshaping toxicology.

    The passage of the Federal Food, Drug, and Cosmetic Act in 1938 mandated animal testing for the development of safe and effective drugs for human use.

    prostate512x288
    Integrating live-cell imaging with optimized organoid pipelines for prostate cancer drug testing.

    Tumor organoids are becoming increasingly popular advanced model systems for in vitro cancer drug testing. Typically established from patient tumor samples or patient-derived xenografts (PDXs), these 3D cell cultures can replicate the genetic and molecular features of the original tumor.

    Unlocking the potential of organoids
    Unlocking the potential of organoids: the power of standardization and automation.

    Interest in organoids has increased dramatically over the past decade, driven by their remarkable ability to self-organize into complex structures that closely resemble their biological counterparts.

    bioprinting-workflow
    Bioprinting workflow enables high-throughput drug discovery in 3D cell cultures.

    Drug discovery can be a long and expensive process, so researchers are always looking for ways to optimize and enhance workflows.

    3d-cellularimaging-blog
    3D cellular imaging: some critical factors for success.

    Since its introduction in the early 1990s to today, 3-dimensional (3D) imaging still remains a “buzz” word that sounds a bit mysterious.

    Questions?
    We're here to help.

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