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  • Altered Cellular Processes
    • Altered Cellular Processes
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    • Protein Aggregation

Altered Cellular Processes

Investigate cellular processes and discover potential therapeutic targets

The central nervous system (CNS) is a complex biological system with unique anatomical and physiological characteristics. Although there is still much to be discovered behind the workings of the brain, researchers have pointed to aberrant changes in key cellular processes that contribute to the mechanisms of neurodegenerative disease progression. Among these, critical pathways involved in oxidative stress, mitophagy, cell death, proteostasis, neuropeptide or neurotransmitter deregulation, and others are currently being explored.

We offer reagents, consumables, and instruments for immunoassay readouts and high content imaging to better assess these cellular, molecular, and/or phenotypic changes. Our Opera Phenix® Plus High Content Screening System has been used to assess degrees of oligodendrocyte differentiation, calcium flux, neuroprotective effects of certain compounds, neurite growth, and other neurological features with fixed or live-cell imaging.

For research use only. Not for use in diagnostic procedures.

Altered Cellular Processes

Explore Immunoassays by target class

cytokine research reagents

Cytokine Research Reagents

Cytokines regulate several physiological and pathological roles including innate immunity, acquired immunity, and many inflammatory responses.
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targeted protein degradation

Targeted Protein Degradation

Protein homeostasis in the cellular environment is achieved through the ubiquitin-proteasome system (UPS) and the autophagy-lysosomal system (ALS).
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biomarker detection reagents

Biomarker detection reagents

Our biomarker detection reagents and kits are designed to excel in applications that rely on high sensitivity, wide dynamic range, and easy automation.
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Protein Kinase 512x288

Protein kinase research reagents

The human kinome comprises 518 protein kinases and 20 lipid kinases.
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epigenetic research reagents

Epigenetic research reagents

The epigenetics’ field revolutionized the understanding of heredity.
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gpcr research reagents

GPCR research reagents

G protein-coupled receptors (GPCRs) are the largest family of membrane proteins and the most studied targets in drug discovery. They relay extracellular signals by triggering intracellular pathways through coupling with G proteins and arrestins.
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protein protein interaction research reagents

Protein-protein interaction research reagents

The interactions and binding of proteins are implicated in a large number of biological processes. The need for efficient, highly sensitive assays to study large protein interactions is increasingly important.
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Featured products

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Cellular Imaging & Analysis

Answer complex cell biology questions with powerful cellular imaging and analysis solutions, including systems, reagents, microplates, software and automation.

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microplate readers

Microplate Readers

As many of you know, microplate readers are instruments used to detect biological, chemical, biochemical or physical events from samples in a microplate.
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